• Non-invasive DXA Scan less than 25 seconds

  BMD and body composition are commonly reported measures for physiological monitoring. Invasive methods have traditionally been used to determine BMD and body composition, requiring post-mortem studies in small animals. For these purposes, destructive testing, mechanical tests, and ash measurements to reveal chemical composition have been applied. These methods are time consuming, destructive and require sacrificing the animal. Therefore, rapid, quantitative and non-invasive alternatives are desirable.

  DXA based imaging device, iNSiGHT, measures BMD and assesses body composition of animal in vivo for a longitudinal investigation to monitor changes in whole body composition with growth and aging in animal. Using non-invasive measurement and analysis method, it is able for iNSiGHT to repeatedly scan cohorts of animal over long-term study.

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• Proved Precision and Accuracy

  iNSiGHT’s precision, accuracy and capability of detecting changes for the measurements of total-body weight, fat weight, and lean weight in an 8-week follow-up study of rats was proved by a clinical trial (Yeu et al. Laboratory Animal Research (2019) 35:2)

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• DR Imaging by Flat Panel Detector and Color Mapping by DXA Analysis

  iNSiGHT presents an ultimate DXA image with high resolution of 100μm. DR image and Color Mapping for lean and fat distribution is optimized for visual analysis and assessment. As pivotal tools enabling a genuine longitudinal study, iNSiGHT is equipped with Multiple ROI setting and the History Analysis.

  Transparent window and wide imaging area of 16.5cmX25.5cm secure measuring environment and process for in vivo imaging and DXA analysis. Magnification shelf supports high-end imaging analysis up to 4X geometric magnification.

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Ultimate In Vivo Imaging and Automatic DXA Analysis for Longitudinal Studies

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  Sample images of two diet groups. Above is a sample of the Normal Diet(ND) group, and below is a sample of the High Fat Diet(HFD) group.A., B. and C. are X-ray image, bone enhanced image and color composition image of one mouse in ND group, respectively.
  D., E. and F. are X-ray images, bone enhanced images and color composition images of a mouse in the HFD group, respectively.In a color composition image, fat tissue is shown by red color and lean tissue by green color. From the color composition images of two diet groups, it is possible to tell that the HFD group has a relatively higher DXA Fat Tissue Mass(FTM) compared to the ND group.
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  X-ray Image by iNSiGHT